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M-PEG3-S-PEG3-Boc

M-PEG3-S-PEG3-Boc is a heterobifunctional PEG-based linker featuring a Boc-protected amine and a terminal thiol, commonly used to construct PROTAC molecules for targeted protein degradation. Its flexible, hydrophilic spacer is crucial for optimizing linker length and polarity in both cellular and in vivo PROTAC research to enhance degradation efficiency and pharmacokinetics.

Product Specifications

CAS Number

2055040-96-3

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

O=C (OC (C) (C) C) CCOCCOCCOCCSCCOCCOCCOC

Molecular Formula

C20H40O8S

Molecular Weight

440.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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