Mal-C6-α-Amanitin
Mal-C6-α-Amanitin is an ADC linker-drug conjugate that delivers the potent RNA polymerase II inhibitor α-Amanitin to target cells. This construct enables research into targeted cancer therapies, demonstrating significant antitumor activity in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1578249-76-9
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@@H] (O) CN1C (=O) [C@] ([H]) (CC (N) =O) NC (=O) [C@]1 ([H]) CS (=O) c3[nH]c4cc (OCCCCCCNC (=O) CCCCCN5C (=O) C=CC5=O) ccc4c3C[C@] ([H]) (NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) [C@@H] (O) CO) C (=O) NCC (=O) N[C@@] ([H]) ([C@@H] (C) CC) C (=O) NCC (=O) N1
Molecular Formula
C55H78N12O17S
Molecular Weight
1211.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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