MAL-di-EG-Val-Cit-PAB-MMAF
This product is a conjugate of the protease-cleavable linker MAL-di-EG-Val-Cit-PAB and the cytotoxic payload MMAF (Monomethyl auristatin F) . It is widely used in ADC (Antibody-Drug Conjugate) research for targeted cancer therapy, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
CN ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (N1CCC[C@@]1 ([H]) [C@H] (OC) [C@@H] (C) C (N[C@@H] (CC2=CC=CC=C2) C (O) =O) =O) =O) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) N (C) C (OCC3=CC=C (NC ([C@H] (CCCNC (N) =O) NC ([C@H] (C (C) C) NC (CCOCCOCCNC (CCN4C (C=CC4=O) =O) =O) =O) =O) =O) C=C3) =O
Molecular Formula
C73H113N13O19
Molecular Weight
1476.75
Storage Conditions
-20°C
Notes
For research use only.
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