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Mal-PEG4-VA-PBD

Mal-PEG4-VA-PBD is a cleavable linker-payload conjugate designed for constructing Antibody-Drug Conjugates (ADCs) . It incorporates the potent DNA-crosslinking agent pyrrolobenzodiazepine (PBD), enabling targeted cytotoxicity. This conjugate is widely used in ADC research for evaluating antitumor efficacy in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1342820-68-1

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

O=C1N2[C@@] (CC (=C2) C3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCNC (CCN4C (=O) C=CC4=O) =O) =O) C (C) C) =O) C) =O) C=C3) (C=NC=5C1=CC (OC) =C (OCCCOC6=C (OC) C=C7C (=C6) N=C[C@]8 (N (C7=O) C=C (C8) C9=CC=C (OC) C=C9) [H]) C5) [H]

Molecular Formula

C68H79N9O17

Molecular Weight

1294.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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