Mal-PEG4-VA-PBD
Mal-PEG4-VA-PBD is a cleavable linker-payload conjugate designed for constructing Antibody-Drug Conjugates (ADCs) . It incorporates the potent DNA-crosslinking agent pyrrolobenzodiazepine (PBD), enabling targeted cytotoxicity. This conjugate is widely used in ADC research for evaluating antitumor efficacy in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1342820-68-1
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
O=C1N2[C@@] (CC (=C2) C3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCNC (CCN4C (=O) C=CC4=O) =O) =O) C (C) C) =O) C) =O) C=C3) (C=NC=5C1=CC (OC) =C (OCCCOC6=C (OC) C=C7C (=C6) N=C[C@]8 (N (C7=O) C=C (C8) C9=CC=C (OC) C=C9) [H]) C5) [H]
Molecular Formula
C68H79N9O17
Molecular Weight
1294.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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