Mal-PEG8-Val-Cit-PAB-MMAE
This cleavable linker, featuring an 8-unit polyethylene glycol (PEG) spacer, is designed for constructing antibody-drug conjugates (ADCs) . It enables the targeted delivery and controlled release of potent cytotoxins like MMAE in both in vitro and in vivo cancer research applications.
Product Specifications
CAS Number
2353409-69-3
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[H][C@]1 (CCCN1C (=O) CC (OC) [C@@H] ([C@@H] (C) CC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCOCCOCCOCCOCCOCCOCCOCCOCCN2C (=O) C=CC2=O) C (C) C) cc1) C (C) C) [C@H] (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1 |c:87|
Molecular Formula
C81H131N11O23
Molecular Weight
1626.993
Storage Conditions
-20°C
Notes
For research use only.
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