Mal-Phe-C4-VC-PAB-MMAE
This product is the chemical conjugate of the cytotoxic payload monomethyl auristatin E (MMAE) with a Mal-Phe-C4-VC-PAB linker, designed for constructing antibody-drug conjugates (ADCs) . It is a key reagent for researchers developing targeted cancer therapies and studying ADC mechanisms in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2259318-51-7
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@] ([C@@H] (C) CC) ([C@@H] (CC (=O) N1CCC[C@@]1 ([H]) [C@H] (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1) OC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCc2ccc (cc2) N2C (=O) C=CC2=O) C (C) C) cc1) C (C) C
Molecular Formula
C72H105N11O15
Molecular Weight
1364.67
Storage Conditions
-20°C
Notes
For research use only.
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