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Mal-Phe-C4-VC-PAB-MMAE

This product is the chemical conjugate of the cytotoxic payload monomethyl auristatin E (MMAE) with a Mal-Phe-C4-VC-PAB linker, designed for constructing antibody-drug conjugates (ADCs) . It is a key reagent for researchers developing targeted cancer therapies and studying ADC mechanisms in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2259318-51-7

Field of Research

Pharmacology & Drug Discovery

Smiles

[H][C@] ([C@@H] (C) CC) ([C@@H] (CC (=O) N1CCC[C@@]1 ([H]) [C@H] (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1) OC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCc2ccc (cc2) N2C (=O) C=CC2=O) C (C) C) cc1) C (C) C

Molecular Formula

C72H105N11O15

Molecular Weight

1364.67

Storage Conditions

-20°C

Notes

For research use only.

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