Mal-VC-PAB-DM1
Mal-VC-PAB-DM1 is a cleavable drug-linker conjugate for constructing antibody-drug conjugates (ADCs) . It incorporates the cytotoxic maytansinoid DM1, which disrupts microtubule dynamics, enabling targeted delivery and potent antitumor activity in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
1464051-44-2
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@@] (O) (NC (=O) O1) [C@] ([H]) (OC) \C=C/C=C (C) \Cc1cc (OC) c (Cl) c (c1) N (C) C (=O) C[C@] ([H]) (OC (=O) [C@H] (C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCCN3C (=O) C=CC3=O) C (C) C) cc1) [C@]1 (C) O[C@H]1[C@@H]2C
Molecular Formula
C61H82ClN9O17
Molecular Weight
1248.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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