Mc-MMAD
Mc-MMAD is a maleimidocaproyl-modified derivative of the potent tubulin inhibitor monomethyl auristatin D (MMAD) . This cytotoxic payload is widely utilized in antibody-drug conjugate (ADC) research for targeted cancer therapy, enabling the evaluation of drug efficacy in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1401963-15-2
Product Name Alternative
Auristatin, DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, Mc MMAD, McMMAD, Mc-MMAD
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.07 mM) ; DMSO:≥ 80 mg/mL
Smiles
[H][C@] ([C@@H] (C) CC) ([C@@H] (CC (=O) N1CCC[C@H]1[C@H] (OC) [C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) c1nccs1) OC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) CCCCCN1C (=O) C=CC1=O) C (C) C
Molecular Formula
C51H77N7O9S
Molecular Weight
964.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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