MC-Sq-Cit-PAB-Dolastatin10
MC-Sq-Cit-PAB-Dolastatin10 is an ADC linker-payload conjugate incorporating the potent antimitotic agent Dolastatin 10. This research compound is utilized in the development of antibody-drug conjugates for targeted cancer therapy and has been investigated in both in vitro cytotoxicity assays and in vivo preclinical tumor models.
Product Specifications
CAS Number
1941168-65-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (N[C@H] (C (NC1=CC=C (C[N+] ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] (CC3=CC=CC=C3) C4=NC=CS4) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) [C@@H] (C) C) (C) C) C=C1) =O) CCCNC (N) =O) (=O) C5 (C (NCCCCCN6C (=O) C=CC6=O) =O) CCC5
Molecular Formula
C70H105N12O12S
Molecular Weight
1338.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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