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MC-VC (S) -PABQ-Tubulysin M

MC-Val-Cit-PAB-tubulysin5a is an antibody-drug conjugate (ADC) linker-payload featuring the potent tubulin inhibitor tubulysin5a. This cleavable conjugate is designed for the development of ADCs with targeted antitumor activity, applicable in both in vitro cytotoxicity assays and in vivo xenograft model studies.

Product Specifications

CAS Number

2055896-86-9

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (N[C@H] (C (N ([C@H] (C[C@@H] (OC (C) =O) C1=NC (C (N[C@@H] (CC2=CC=CC=C2) C[C@@H] (C (O) =O) C) =O) =CS1) C (C) C) C) =O) [C@H] (CC) C) (=O) [C@@H]3[N+] (CC4=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN5C (=O) C=CC5=O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C4) (C) CCCC3

Molecular Formula

C66H96N11O13S

Molecular Weight

1283.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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