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N- (Mal-PEG6) -N-bis (PEG7-TCO)

This heterobifunctional polyethylene glycol (PEG) linker is designed for constructing PROTAC molecules. Its maleimide and trans-cyclooctene (TCO) groups enable conjugation to thiol- and tetrazine-bearing warheads, facilitating the development of degraders for in vitro and in vivo target validation studies.

Product Specifications

CAS Number

2093152-84-0

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (CCOCCOCCOCCOCCNC (=O) OC1CCCC=CCC1) NCCOCCOCCOCCN (CCOCCOCCOCCNC (=O) CCOCCOCCOCCOCCNC (=O) OC1CCCC=CCC1) C (=O) CCOCCOCCOCCOCCOCCOCCNC (=O) CCN1C (=O) C=CC1=O |w:25.25,78.79, c:113|

Molecular Formula

C78H137N7O30

Molecular Weight

1652.973

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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