PAC
This product is a PAC (PROTAC Antibody Conjugate), which combines an antibody-drug conjugate linker with a PROTAC to target the estrogen receptor-alpha (ERα) . It demonstrates superior ERα degradation compared to the PROTAC alone, making it a valuable tool for investigating targeted protein degradation in both cellular and in vivo breast cancer models.
Product Specifications
CAS Number
2158322-33-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CCC (=C (c1ccc (OCCN (C) C (=O) COCCOCCNC (=O) c2ccc (cc2) C (=O) N2[C@@H] (C) [C@H] (NC (=O) [C@H] (C) NC) C (=O) N (Cc3c (OC) ccc4ccccc34) c3ccc (cc23) C#N) cc1) c1ccc (OCc2ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCCN3C (=O) C=CC3=O) C (C) C) cc2) cc1) c1ccccc1 |w:3.3, c:112|
Molecular Formula
C94H107N13O16
Molecular Weight
1674.965
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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