PDdEC-NB
PDdEC-NB is a cleavable linker designed for constructing antibody-drug conjugates (ADCs) . Its disulfide bond is selectively reduced in the intracellular environment, facilitating targeted drug release. This mechanism is utilized in both in vitro cytotoxicity assays and in vivo preclinical studies of ADC therapeutics.
Product Specifications
CAS Number
1956318-90-3
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (OC1=CC=C (C=C1) N (=O) =O) OCC (SSC2=NC=CC=C2) (C) C
Molecular Formula
C16H16N2O5S2
Molecular Weight
380.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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