DFKBP-1
DFKBP-1 is a potent PROTAC degrader of FKBP12, constructed by conjugating the SLF ligand for FKBP12 to a thalidomide-based cereblon ligand via a linker. This bifunctional molecule enables targeted protein degradation and is a valuable chemical tool for studying FKBP12 biology in both cellular and in vivo research contexts.
Product Specifications
CAS Number
1799711-22-0
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCC (NCCCCNC (CCC (NC4=CC ([C@H] (OC (=O) [C@H]5N (C (C (C (CC) (C) C) =O) =O) CCCC5) CCC6=CC (OC) =C (OC) C=C6) =CC=C4) =O) =O) =O
Molecular Formula
C53H64N6O14
Molecular Weight
1009.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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