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Desmethyl-QCA276

This product features Desmethyl-QCA276, a derivative of the potent BET inhibitor QCA276 (IC50=10 nM; Ki=2.3 nM), designed as a cereblon-binding PROTAC for targeted BET protein degradation. It serves as a chemical tool for investigating BET biology and targeted protein degradation in both cellular and in vivo research models.

Product Specifications

CAS Number

2126819-55-2

Field of Research

Pharmacology & Drug Discovery

Smiles

C (#CC=1SC2=C (C1CC=3C=CC=CC3) COCC4=NN=C (N42) C) C=5C=NNC5

Molecular Formula

C21H17N5OS

Molecular Weight

387.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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