Desmethyl-QCA276
This product features Desmethyl-QCA276, a derivative of the potent BET inhibitor QCA276 (IC50=10 nM; Ki=2.3 nM), designed as a cereblon-binding PROTAC for targeted BET protein degradation. It serves as a chemical tool for investigating BET biology and targeted protein degradation in both cellular and in vivo research models.
Product Specifications
CAS Number
2126819-55-2
Field of Research
Pharmacology & Drug Discovery
Smiles
C (#CC=1SC2=C (C1CC=3C=CC=CC3) COCC4=NN=C (N42) C) C=5C=NNC5
Molecular Formula
C21H17N5OS
Molecular Weight
387.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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