PROTAC BRD4 degrader for PAC-1
This PROTAC molecule is a chimeric degrader that selectively targets BRD4 for proteasomal degradation via a disulfide-containing linker. It is a valuable chemical tool for investigating BET protein function and targeted protein degradation in both cellular and in vivo research contexts.
Product Specifications
Field of Research
Metabolism Research; Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C (C1=C (CS (=O) (C) =O) C=C (C (N (C2=NC=C (F) C=C2F) C3) =C1) C4=CN (C) C (C5=C4C3=CN5) =O) NCCCCCCCCCCC (N[C@@H] (C (C) (C) C) C (N6[C@H] (C (NCC7=CC=C (C8=C (C) N=CS8) C=C7) =O) C[C@@H] (OC (OCC (C) (C) SS (C) (=O) =O) =O) C6) =O) =O
Molecular Formula
C62H77F2N9O12S4
Molecular Weight
1306.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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