PROTAC ER Degrader-3
PROTAC ER Degrader-3 (LP2) is a synthetic intermediate for PAC, a linker used in constructing antibody-drug conjugates (ADCs) and PROTACs. When conjugated to an antibody, the resulting PAC-antibody complex demonstrates enhanced ERα degradation in research settings compared to unconjugated PROTAC molecules, as supported by published studies.
Product Specifications
CAS Number
2158322-29-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CCC (=C (c1ccc (O) cc1) c1ccc (OCCN (C) C (=O) COCCOCCNC (=O) c2ccc (cc2) C (=O) N2[C@@H] (C) [C@H] (NC (=O) [C@H] (C) N (C) C (=O) OC (C) (C) C) C (=O) N (Cc3c (OC) ccc4ccccc34) c3ccc (cc23) C#N) cc1) c1ccccc1 |w:3.11|
Molecular Formula
C71H77N7O12
Molecular Weight
1220.434
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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