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PROTAC FKBP Degrader-3

PROTAC FKBP Degrader-3 is a heterobifunctional molecule consisting of an FKBP12 ligand linked to a VHL E3 ligase recruiter, designed to induce targeted protein degradation. This compound serves as a valuable chemical tool for studying FKBP12 biology and PROTAC mechanism in cellular and biochemical assays.

Product Specifications

CAS Number

2079056-43-0

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Smiles

[C@H] (C (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (OCC (NCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C=6SC=NC6C) =O) C[C@@H] (O) C4) C (C) (C) C) =O) =O) =CC=C3) =O) CCCC1) (CC) C7=CC (OC) =C (OC) C (OC) =C7

Molecular Formula

C68H90N6O17S

Molecular Weight

1295.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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