PROTAC RAR Degrader-1
PROTAC RAR Degrader-1 is a heterobifunctional degrader that recruits cIAP1 to target the retinoic acid receptor (RAR) for proteasomal degradation. As a SNIPER, it induces maximal RAR degradation at 30 μM in HT1080 cells and serves as a tool for studying RAR function in cancer and differentiation research.
Product Specifications
CAS Number
1351169-27-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O (CCCNC (COCCOCCOCCNC ([C@@H] (NC ([C@H] ([C@@H] (CC1=CC=CC=C1) N) O) =O) CC (C) C) =O) =O) C2=C (C (O) =O) C=CC (/C=C/C (=O) C3=CC (C (C) (C) C) =CC (C (C) (C) C) =C3) =C2
Molecular Formula
C51H72N4O11
Molecular Weight
917.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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