SirReal1-O-propargyl
SirReal1-O-propargyl is a potent and selective Sirtuin 2 (SIRT2) inhibitor with an IC50 of 2.4 μM. It serves as a versatile PROTAC ligand, and its propargyl moiety facilitates click chemistry conjugation for probe development. This compound is a valuable tool for studying SIRT2 biology in cellular and biochemical assays.
Product Specifications
CAS Number
1862237-99-7
Product Name Alternative
IC50: 2.4 μM (Sirt2), SirReal1-O-propargyl, SirReal-1-O-propargyl, SirReal1 O propargyl, SirReal1Opropargyl, PROTAC Sirt2-binding moiety 1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.97% (May vary between batches)
Smiles
O=C (NC1=NC=C (S1) CC=2C=CC=C (OCC#C) C2) CSC=3N=C (C=C (N3) C) C
Molecular Formula
C21H20N4O2S2
Molecular Weight
424.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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