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SirReal1-O-propargyl

SirReal1-O-propargyl is a potent and selective Sirtuin 2 (SIRT2) inhibitor with an IC50 of 2.4 μM. It serves as a versatile PROTAC ligand, and its propargyl moiety facilitates click chemistry conjugation for probe development. This compound is a valuable tool for studying SIRT2 biology in cellular and biochemical assays.

Product Specifications

CAS Number

1862237-99-7

Product Name Alternative

IC50: 2.4 μM (Sirt2), SirReal1-O-propargyl, SirReal-1-O-propargyl, SirReal1 O propargyl, SirReal1Opropargyl, PROTAC Sirt2-binding moiety 1

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.97% (May vary between batches)

Smiles

O=C (NC1=NC=C (S1) CC=2C=CC=C (OCC#C) C2) CSC=3N=C (C=C (N3) C) C

Molecular Formula

C21H20N4O2S2

Molecular Weight

424.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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