(S, R, S) -AHPC-C4-NH2
This custom-synthesized conjugate features a VHL E3 ligase ligand based on (S, R, S) -AHPC, connected via a C4 linker designed for constructing EED-targeting PROTAC molecules. It serves as a key component for developing bifunctional degraders to probe EED function in epigenetic research and for evaluating targeted protein degradation in cellular assays.
Product Specifications
CAS Number
2138439-53-7
Field of Research
Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (CCCCN) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C27H39N5O4S
Molecular Weight
529.7
Storage Conditions
-20°C
Notes
For research use only.
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