(S, R, S) -AHPC-Me-C10-Br
This chemically synthesized PROTAC ligand-linker conjugate incorporates an MS432-based MEK1/2 inhibitor linked to a VHL E3 ligase binder. It serves as a key component for constructing bifunctional degraders to probe MEK protein function and degradation pathways in both cellular and in vivo research contexts.
Product Specifications
CAS Number
2836297-55-1
Product Name Alternative
(S, R, S) AHPC Me C10 Br, (S, R, S) AHPCMeC10Br, (S, R, S) -AHPC-Me-C-10-Br, AHPC-Me-C10-Br
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.89% (May vary between batches)
Solubility
DMSO:80 mg/mL (115.65 mM)
Smiles
C ([C@@H] (NC (CCCCCCCCCCBr) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (N[C@@H] (C) C2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C34H51BrN4O4S
Molecular Weight
691.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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