(S, R, S) -AHPC-Me-C10-Br
This chemically synthesized PROTAC ligand-linker conjugate incorporates an MS432-based MEK1/2 inhibitor linked to a VHL E3 ligase binder. It serves as a key component for constructing bifunctional degraders to probe MEK protein function and degradation pathways in both cellular and in vivo research contexts.
Product Specifications
CAS Number
2836297-55-1
Product Name Alternative
(S, R, S) AHPC Me C10 Br, (S, R, S) AHPCMeC10Br, (S, R, S) -AHPC-Me-C-10-Br, AHPC-Me-C10-Br
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.89% (May vary between batches)
Solubility
DMSO:80 mg/mL (115.65 mM)
Smiles
C ([C@@H] (NC (CCCCCCCCCCBr) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (N[C@@H] (C) C2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C34H51BrN4O4S
Molecular Weight
691.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR206804L3V 200 µL
Ippk (BC024630) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 