SC-VC-PAB-DM1
SC-VC-PAB-DM1 is a cleavable linker-drug conjugate for constructing Antibody-Drug Conjugates (ADCs) . It releases the potent maytansinoid DM1, a microtubule-disrupting agent, enabling targeted cytotoxicity in cancer research. This conjugate is widely used in preclinical in vitro and in vivo studies to evaluate ADC efficacy and therapeutic potential.
Product Specifications
CAS Number
2259318-47-1
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12O[C@@]1 (C) [C@H] (CC (=O) N (C) c1cc (C\C (C) =C/C=C/[C@@H] (OC) [C@@]3 (O) C[C@] ([H]) (OC (=O) N3) [C@H]2C) cc (OC) c1Cl) OC (=O) [C@H] (C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCC (=O) ON2C (=O) CCC2=O) C (C) C) cc1 |c:17, t:19|
Molecular Formula
C61H82ClN9O19
Molecular Weight
1280.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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