SJFδ
SJFδ is a 10-atom linker PROTAC molecule that induces selective degradation of p38δ with a DC50 of 46.17 nM, sparing other p38 isoforms. This tool compound is valuable for in vitro and in vivo research to investigate p38δ-specific signaling pathways in inflammation and oncology.
Product Specifications
CAS Number
2254609-23-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (NC1=CC (F) =C (OC=2C3=C (C=C (OCCOCCOCCOC4=C (CNC (=O) [C@H]5N (C ([C@H] (C (C) C) N6CC=7C (C6=O) =CC=CC7) =O) C[C@H] (O) C5) C=CC (=C4) C=8SC=NC8C) C (OC) =C3) N=CC2) C=C1) (=O) C9 (C (NC%10=CC=C (F) C=C%10) =O) CC9
Molecular Formula
C62H63F2N7O12S
Molecular Weight
1168.27
Storage Conditions
-20°C
Notes
For research use only.
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