DBA-DM4
DBA-DM4 is a drug-linker conjugate designed for synthesizing antibody-drug conjugates (ADCs), specifically coupling the cytotoxic maytansinoid DM1 via an SPDP linker. This construct is widely used in cancer research to develop targeted therapeutics, with applications in both in vitro cytotoxicity assays and in vivo preclinical studies of ADC efficacy.
Product Specifications
CAS Number
905449-84-5
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12O[C@@]1 (C) [C@H] (CC (=O) N (C) c1cc (C\C (C) =C/C=C/[C@@H] (OC) [C@@]3 (O) C[C@] ([H]) (OC (=O) N3) [C@H]2C) cc (OC) c1Cl) OC (=O) [C@H] (C) N (C) C (=O) CCC (C) (C) SSCCCC (O) =O |c:17, t:19|
Molecular Formula
C42H60ClN3O12S2
Molecular Weight
898.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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