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Tetrazine-PEG4-SS-NHS

Tetrazine-PEG4-SS-NHS is a cleavable linker for constructing antibody-drug conjugates (ADCs) . Its disulfide bond enables glutathione-mediated release in reducing environments like the cytoplasm, while the PEG spacer enhances solubility. This linker is utilized in both in vitro assay development and in vivo targeted cancer therapy research.

Product Specifications

Product Name Alternative

Cleavable, ADCLinker, ADC Linker, ADC linker, TetrazinePEG4SSNHS, Tetrazine-PEG-4-SS-NHS, Tetrazine-PEG4-SS-NHS, Tetrazine PEG4 SS NHS

Purity

95.70% (May vary between batches)

Smiles

O=C (CCSSCCC (=O) ON1C (=O) CCC1=O) NCCOCCOCCOCCOCCC (=O) NCc1ccc (-c2nncnn2) cc1

Molecular Formula

C30H41N7O10S2

Molecular Weight

723.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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