Tetrazine-PEG4-SS-NHS
Tetrazine-PEG4-SS-NHS is a cleavable linker for constructing antibody-drug conjugates (ADCs) . Its disulfide bond enables glutathione-mediated release in reducing environments like the cytoplasm, while the PEG spacer enhances solubility. This linker is utilized in both in vitro assay development and in vivo targeted cancer therapy research.
Product Specifications
Product Name Alternative
Cleavable, ADCLinker, ADC Linker, ADC linker, TetrazinePEG4SSNHS, Tetrazine-PEG-4-SS-NHS, Tetrazine-PEG4-SS-NHS, Tetrazine PEG4 SS NHS
Purity
95.70% (May vary between batches)
Smiles
O=C (CCSSCCC (=O) ON1C (=O) CCC1=O) NCCOCCOCCOCCOCCC (=O) NCc1ccc (-c2nncnn2) cc1
Molecular Formula
C30H41N7O10S2
Molecular Weight
723.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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