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Thalidomide-NH-C4-NH2 TFA

Thalidomide-NH-C4-NH2 TFA (compound 29c) is a cereblon E3 ligase ligand-linker conjugate used to construct PROTAC molecules. It serves as a key component in the potent and selective BET degrader PROTAC BRD2/BRD4 degrader-1, enabling targeted protein degradation research in both cellular and in vivo studies.

Product Specifications

CAS Number

2093387-50-7

Field of Research

Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Smiles

O=C (O) C (F) (F) F.O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCCCN) C3C2=O) CC1

Molecular Formula

C19H21F3N4O6

Molecular Weight

458.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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