1- (2'-O-4-C-Methylene-beta-D-ribofuranosyl) thymine

This bicyclic nucleoside analog, featuring a methylene bridge between the C-4' and O-2' positions of the ribose ring, is a chemically modified derivative of thymidine. It serves as a valuable research tool in nucleic acid chemistry for studying oligonucleotide stability and conformation, with applications in both in vitro biochemical assays and the development of antisense or siRNA therapeutics.