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C-Kit-IN-3 maleate

C-Kit-IN-3 maleate is a highly potent and selective inhibitor of c-KIT kinase, demonstrating IC50 values of 4 nM for wild-type and 8 nM for the T670I mutant. This compound is a valuable research tool for investigating c-KIT-driven pathologies, such as gastrointestinal stromal tumors (GIST), in both cellular and animal model studies.

Product Specifications

Field of Research

Signal Transduction

Smiles

O=C (O) /C=C\C (O) =O.O=C (NC1=CC=C (OC2=CC=NC3=CC (OC) =C (OC) C=C23) C=C1) CC4=CC=C (Cl) C (C (F) (F) F) =C4

Molecular Formula

C30H24ClF3N2O8

Molecular Weight

632.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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