ESM156
ESM156 is a potent and selective FLT3 inhibitor with an IC50 of 1.4 nM. It demonstrates strong antiproliferative effects in AML cell lines, including MV4-11 (EC50 = 150 nM) and MOLM-13 (EC50 = 40 nM) . This compound is a valuable research tool for investigating FLT3-driven malignancies in both in vitro and in vivo models.
Product Specifications
Smiles
CNC1=NC=C2C (N (CC3CCCC3) N=C2C4=CC=C (N5CCN (C) CC5) C=C4) =N1
Molecular Formula
C23H31N7
Molecular Weight
405.55
Storage Conditions
-20°C
Notes
For research use only.
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