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KNI-1657

KNI-1657 is a highly potent and selective HIV-1 protease inhibitor, demonstrating significant activity against the pNL4-3 strain with an EC50 of 3 nM. It is particularly effective against lopinavir-resistant HIV-1 variants, making it a valuable tool for antiviral research in both in vitro enzyme inhibition and cell-based assays.

Product Specifications

Smiles

O=C ([C@H]1N (C ([C@@H] (O) [C@@H] (NC ([C@@H] (NC (C2=CC3=CC=CC (OC) =C3O2) =O) [C@@H]4COCC4) =O) CC5=CC=CC=C5) =O) CSC1 (C) C) NCC6=C (C) C=CC=C6C

Molecular Formula

C41H48N4O8S

Molecular Weight

756.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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