DL-Acetylshikonin
DL-Acetylshikonin is a non-selective, reversible cytochrome P450 inhibitor with IC50 values of 1.4-4.0 μM. DL-Acetylshikonin has anti-cancer and anti-inflammatory activities[1].
Product Specifications
CAS Number
54984-93-9
UNSPSC
12352005
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dl-acetylshikonin.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\CC(OC(C)=O)C1=CC(C2=C(O)C=CC(O)=C2C1=O)=O
Molecular Formula
C18H18O6
Molecular Weight
330.33
References & Citations
[1]Shon JC, et al. Acetylshikonin is a novel non-selective cytochrome P450 inhibitor. Biopharm Drug Dispos. 2017 Dec;38 (9) :553-556.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP1; CYP2; CYP3
Frequently Asked Questions
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