H 77
H 77 is a potent renin inhibitor derived from the angiotensinogen (6-13) octapeptide, featuring a reduced peptide bond (-CH2-NH-) replacing the standard Leu (10) -Leu (11) linkage. This analog is utilized in cardiovascular research to study the renin-angiotensin system in both in vitro biochemical assays and in vivo hypertension models.
Product Specifications
CAS Number
82131-82-6
Smiles
C (N[C@@H] (CC1=CC=CC=C1) C (N[C@@H] (CC2=CN=CN2) C (N[C@H] (CN[C@H] (C (N[C@H] (C (N[C@@H] (CC3=CC=C (O) C=C3) C (O) =O) =O) C (C) C) =O) CC (C) C) CC (C) C) =O) =O) (=O) [C@H]4N (C ([C@@H] (CC5=CN=CN5) N) =O) CCC4
Molecular Formula
C52H74N12O9
Molecular Weight
1011.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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