Methotrexate Diglutamate
Methotrexate diglutamate is a small molecule metabolite of methotrexate found in the liver. It acts as a potent inhibitor of human dihydrofolate reductase (DHFR), making it a valuable tool for studying antifolate mechanisms in cancer research and in biochemical assays investigating nucleotide synthesis.
Product Specifications
CAS Number
41600-13-9
Product Name Alternative
DHFR, NSC269401, NSC-269401, NSC 269401
Field of Research
Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.51% (May vary between batches)
Solubility
DMSO:100 mg/mL (171.36 mM)
Smiles
NC=1C2=C (N=CC (CN (C) C3=CC=C (C (N[C@@H] (CCC (N[C@@H] (CCC (O) =O) C (O) =O) =O) C (O) =O) =O) C=C3) =N2) N=C (N) N1
Molecular Formula
C25H29N9O8
Molecular Weight
583.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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