A 83586C
A-83586C is a Streptomyces-derived depsipeptide antibiotic with potent in vitro activity against Gram-positive bacteria. This compound is a research tool that potently inhibits β-catenin/TCF4 signaling and E2F-mediated transcription in cancer cells, downregulating targets like osteopontin and E2F1 while modulating retinoblastoma protein phosphorylation. Its mechanisms support investigations in oncology, particularly in Wnt signaling and cell cycle pathways.
Product Specifications
CAS Number
116364-81-9
Field of Research
Infectious Disease & Virology
Smiles
[C@@] (C (N[C@H]1[C@H] (C (C) C) OC (=O) [C@@] ([C@H] (C) O) (NC (=O) [C@]2 (N (C (=O) [C@@H] (C) N (C) C (=O) [C@H] (C) N (O) C (=O) [C@@]3 (N (C1=O) NCCC3) [H]) NCCC2) [H]) [H]) =O) (CC) (O) [C@]4 (O) O[C@H] (\C (=C\[C@@H] (C (/C (=C/C) /C) =O) C) \C) [C@@H] (C) CC4
Molecular Formula
C47H76N8O14
Molecular Weight
977.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
