AM-1430
AM-1430 is a potent and selective PI3Kδ inhibitor with sub-nanomolar cellular activity (pAKT IC50 = 0.8 nM) . It demonstrates robust in vivo efficacy in rat models of immune response and has favorable pharmacokinetics, supporting its use in researching B-cell and immune-related disorders.
Product Specifications
Smiles
CNC (C1=C (C2=NC=CC=C2) C ([C@H] (C) NC3=NC=NC (N) =C3C#N) =NC4=CC=CC (F) =C14) =O
Molecular Formula
C23H19FN8O
Molecular Weight
442.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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