AZ12971554
AZ12971554 is a potent, selective small-molecule inhibitor of human thrombin with a Ki of 0.3 nM. It demonstrates anticoagulant activity in human plasma, as shown by its IC50 values in APTT (0.68 μM) and ECT (0.16 μM) assays. This compound is a valuable research tool for studying thrombosis and hemostasis in biochemical and pharmacological experiments.
Product Specifications
Smiles
O=C ([C@@H]1CC=NN1C ([C@@H] (C2=CC=C (F) C=C2) O) =O) NCC3=CC (Cl) =CC=C3N4N=NN=C4
Molecular Formula
C20H17ClFN7O3
Molecular Weight
457.85
Storage Conditions
-20°C
Notes
For research use only.
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