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TRC-19

TRC-19 is a highly potent and selective small molecule inhibitor of Toxoplasma gondii dihydrofolate reductase (DHFR), exhibiting an IC50 of 9 nM with 89-fold selectivity over the human enzyme. This compound is a valuable chemical tool for studying toxoplasmosis, enabling both in vitro enzymatic assays and research into anti-parasitic mechanisms.

Product Specifications

Smiles

NC1=C (N2CCN (C3=CC (C4=CC=CC=C4) =CC=C3) CC2) C=NC (N) =N1

Molecular Formula

C20H22N6

Molecular Weight

346.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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