UK-122 TFA salt
UK-122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 20 nM and a cell-free IC50 of 0.2 μM. It exhibits minimal cytotoxicity (IC50 >100 μM) but significantly impedes the migration and invasion of pancreatic CFPAC-1 cancer cells in vitro, supporting its use in metastasis research.
Product Specifications
CAS Number
1186653-73-5
Field of Research
Immunology & Inflammation, Metabolism Research
Smiles
C (C (O) =O) (F) (F) F.C (=C\1/N=C (OC1=O) C2=CC=CC=C2) \C3=CC=C (C (=N) N) C=C3
Molecular Formula
C19H14F3N3O4
Molecular Weight
405.33
Storage Conditions
-20°C
Notes
For research use only.
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