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UNC3133

UNC3133 is a potent, selective small molecule inhibitor of MerTK (IC50 = 3.0 nM) with additional activity against Axl, Tyro3, and FLT3. Its inhibition disrupts tumor cell survival and reprograms the innate immune response, making it a valuable research tool for studying oncology and immuno-oncology in both cellular and animal models.

Product Specifications

Smiles

OC (CCCC1) CCCCCCCNC2=NC=C3C (N1C=C3C4=CC=C (CN5CCN (C) CC5) C=C4) =N2

Molecular Formula

C30H44N6O

Molecular Weight

504.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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