YM44781
YM44781 is a potent non-peptide antagonist of tachykinin receptors, demonstrating high affinity for both NK1 (pKi = 9.09) and NK2 (pKi = 9.94) subtypes. This compound is a valuable research tool for investigating the role of substance P and neurokinin A in physiological and pathophysiological processes, applicable in both in vitro binding assays and in vivo functional studies.
Product Specifications
CAS Number
173943-29-8
Field of Research
Metabolism Research
Smiles
O=C (C1=CC=C (F) C=C1) N (C) CC (C2=CC=C (Cl) C (Cl) =C2) CCN3CCC4 (NC (=O) CC=5C=CC=CC54) CC3
Molecular Formula
C31H32Cl2FN3O2
Molecular Weight
568.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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