Anti-Mouse 4-1BB/CD137 Antibody (3H3)

Anti-Mouse 4-1BB/CD137 Antibody (3H3) is an anti-mouse 4-1BB/CD137 IgG2a monoclonal antibody. Anti-Mouse 4-1BB/CD137 Antibody (3H3) can effectively activate memory T cells and inhibit tumors by increasing Bcl-xL and granzyme B levels. Anti-Mouse 4-1BB/CD137 Antibody (3H3) can be used for research on cancer such as lymphoma and colon cancer[1][2].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Bcl-2 Family; TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-4-1bb-cd137-antibody-3h3.html

Purity

95.00

Solubility

H2O

Smiles

[Anti-Mouse4-1BB/CD137Antibody(3H3)]

Molecular Weight

(150 kDa)

References & Citations

[1]Lin GH, et al. Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice. PLoS One. 2010 Jun 8;5 (6) :e11003.|[2]Compte M, et al. A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity. Nat Commun. 2018 Nov 15;9 (1) :4809.