Aloe-emodin-8-O-β-D-glucopyranoside
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM[1].
Product Specifications
CAS Number
[33037-46-6]
UNSPSC
12352005
Hazard Statement
H302
Target
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aloe-emodin-8-o-beta-d-glucopyranoside.html
Purity
99.67
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(CO)=CC(O)=C1C2=O)C3=C2C(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)=CC=C3
Molecular Formula
C21H20O10
Molecular Weight
432.38
Precautions
H302
References & Citations
[1]Li S, et al. PTP1B inhibitors from Saussrurea lappa. J Asian Nat Prod Res. 2006 Apr-May;8 (3) :281-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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