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Zaurategrast

Zaurategrast (CT7758) is a potent and oral-effective α4-integrin inhibitor[1].

Product Specifications

CAS Number

[455264-31-0]

Product Name Alternative

CT7758

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zaurategrast.html

Purity

98.07

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(Br)=C(C12CCCCC2)N[C@H](C(O)=O)CC3=CC=C(NC4=NC=CC5=CC=NC=C45)C=C3

Molecular Formula

C26H25BrN4O3

Molecular Weight

521.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hugues Chanteux , et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43 (9) :1381-91.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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